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Effect of PCSK9 inhibition in combination with statin therapy on intracranial atherosclerotic stenosis: A high-resolution MRI study

INTRODUCTION: Intracranial atherosclerotic stenosis (ICAS) is a common cause of stroke worldwide. Evolocumab, a proprotein convertase subtilisin/kexin type-9 inhibitor (PCSK9i), effectively lowers low-density lipoprotein (LDL) and produces favorable changes in coronary atherosclerosis. This study ai...

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Detalles Bibliográficos
Autores principales: Wu, Lingshan, Kong, Qianqian, Huang, Hao, Xu, Shabei, Qu, Wensheng, Zhang, Ping, Yu, Zhiyuan, Luo, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033935/
https://www.ncbi.nlm.nih.gov/pubmed/36967822
http://dx.doi.org/10.3389/fnagi.2023.1127534