TAK1 deficiency promotes liver injury and tumorigenesis via ferroptosis and macrophage cGAS-STING signalling

BACKGROUND & AIMS: Oxidative stress-mediated ferroptosis and macrophage-related inflammation play an important role in various liver diseases. Here, we explored if and how hepatocyte ferroptosis regulates macrophage stimulator of interferon genes (STING) activation in the development of spontane...

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Detalles Bibliográficos
Autores principales: Su, Wantong, Gao, Weicheng, Zhang, Rui, Wang, Qi, Li, Lei, Bu, Qingfa, Xu, Zibo, Liu, Zheng, Wang, Mingming, Zhu, Yaqing, Wu, Guoping, Zhou, Haoming, Wang, Xun, Lu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033999/
https://www.ncbi.nlm.nih.gov/pubmed/36968217
http://dx.doi.org/10.1016/j.jhepr.2023.100695

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