Cargando…

Bulk and single-cell transcriptome analyses of islet tissue unravel gene signatures associated with pyroptosis and immune infiltration in type 2 diabetes

INTRODUCTION: Type 2 diabetes (T2D) is a common chronic heterogeneous metabolic disorder. However, the roles of pyroptosis and infiltrating immune cells in islet dysfunction of patients with T2D have yet to be explored. In this study, we aimed to explore potential crucial genes and pathways associat...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Yaxian, He, Chen, Jiang, Yan, Yang, Mengshi, Xu, Zhao, Yuan, Lingyan, Zhang, Wenhua, Xu, Yushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034023/
https://www.ncbi.nlm.nih.gov/pubmed/36967805
http://dx.doi.org/10.3389/fendo.2023.1132194