Differential expression of epigenetic modifiers in early and late cardiotoxic heart failure reveals DNA methylation as a key regulator of cardiotoxicity

BACKGROUND: Anthracycline-induced cardiotoxicity is a well-known serious clinical entity. However, detailed mechanistic insights on how short-term administration leads to late and long-lasting cardiotoxicity, are still largely undiscovered. We hypothesize that chemotherapy provokes a memory effect a...

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Detalles Bibliográficos
Autores principales: Robinson, Emma L., Ameri, Pietro, Delrue, Leen, Vanderheyden, Marc, Bartunek, Jozef, Altieri, Paola, Heymans, Stephane, Heggermont, Ward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034031/
https://www.ncbi.nlm.nih.gov/pubmed/36970338
http://dx.doi.org/10.3389/fcvm.2023.884174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034031/
https://www.ncbi.nlm.nih.gov/pubmed/36970338
http://dx.doi.org/10.3389/fcvm.2023.884174

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