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Differential expression of epigenetic modifiers in early and late cardiotoxic heart failure reveals DNA methylation as a key regulator of cardiotoxicity
BACKGROUND: Anthracycline-induced cardiotoxicity is a well-known serious clinical entity. However, detailed mechanistic insights on how short-term administration leads to late and long-lasting cardiotoxicity, are still largely undiscovered. We hypothesize that chemotherapy provokes a memory effect a...
Autores principales: | Robinson, Emma L., Ameri, Pietro, Delrue, Leen, Vanderheyden, Marc, Bartunek, Jozef, Altieri, Paola, Heymans, Stephane, Heggermont, Ward A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034031/ https://www.ncbi.nlm.nih.gov/pubmed/36970338 http://dx.doi.org/10.3389/fcvm.2023.884174 |
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