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FES null mice demonstrate a reduction in neutrophil dependent pancreatic cancer metastatic burden

Patients with pancreatic ductal adenocarcinoma (PDAC) have a dismal 5-year survival rate of less than 10%, predominantly due to delayed diagnosis and a lack of effective treatment options. In the PDAC tumor microenvironment (TME), neutrophils are among the immune cell types that are most prevalent a...

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Detalles Bibliográficos
Autores principales: Strøbech, Jan E., Giuriatti, Pietro, Stagaard, Rikke, De Sepulveda, Paulo, Nielsen, Sebastian R., Erler, Janine T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034081/
https://www.ncbi.nlm.nih.gov/pubmed/36969004
http://dx.doi.org/10.3389/fonc.2023.1096499