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FES null mice demonstrate a reduction in neutrophil dependent pancreatic cancer metastatic burden
Patients with pancreatic ductal adenocarcinoma (PDAC) have a dismal 5-year survival rate of less than 10%, predominantly due to delayed diagnosis and a lack of effective treatment options. In the PDAC tumor microenvironment (TME), neutrophils are among the immune cell types that are most prevalent a...
Autores principales: | Strøbech, Jan E., Giuriatti, Pietro, Stagaard, Rikke, De Sepulveda, Paulo, Nielsen, Sebastian R., Erler, Janine T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034081/ https://www.ncbi.nlm.nih.gov/pubmed/36969004 http://dx.doi.org/10.3389/fonc.2023.1096499 |
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