Cargando…

From circuits to behavior: Amygdala dysfunction in fragile X syndrome

Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by a repeat expansion mutation in the promotor region of the FMR1 gene resulting in transcriptional silencing and loss of function of fragile X messenger ribonucleoprotein 1 protein (FMRP). FMRP has a well-defined role in the early dev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Svalina, Matthew N., Sullivan, Regina, Restrepo, Diego, Huntsman, Molly M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034113/ https://www.ncbi.nlm.nih.gov/pubmed/36969493 http://dx.doi.org/10.3389/fnint.2023.1128529

Ejemplares similares

The contribution of inhibitory interneurons to circuit dysfunction in Fragile X Syndrome
por: Cea-Del Rio, Christian A., et al.
Publicado: (2014)

Cell-type-specific control of basolateral amygdala neuronal circuits via entorhinal cortex-driven feedforward inhibition
por: Guthman, E Mae, et al.
Publicado: (2020)

Pathological Plasticity in Fragile X Syndrome
por: Martin, Brandon S., et al.
Publicado: (2012)

Hyperexcitability and Loss of Feedforward Inhibition Contribute to Aberrant Plasticity in the Fmr1KO Amygdala
por: Svalina, Matthew N., et al.
Publicado: (2021)

Of Men and Mice: Modeling the Fragile X Syndrome
por: Dahlhaus, Regina
Publicado: (2018)

From Structure to Behavior in Basolateral Amygdala-Hippocampus Circuits
por: Yang, Ying, et al.
Publicado: (2017)

Rett Syndrome and Fragile X Syndrome: Different Etiology With Common Molecular Dysfunctions
por: Bach, Snow, et al.
Publicado: (2021)

Gaboxadol Normalizes Behavioral Abnormalities in a Mouse Model of Fragile X Syndrome
por: Cogram, Patricia, et al.
Publicado: (2019)

Stress Odorant Sensory Response Dysfunction in Drosophila Fragile X Syndrome Mutants
por: Androschuk, Alaura, et al.
Publicado: (2018)

Disrupted inhibitory plasticity and homeostasis in Fragile X syndrome
por: Cea-Del Rio, C.A., et al.
Publicado: (2020)

Auditory Processing in Fragile X Syndrome
por: Rotschafer, Sarah E., et al.
Publicado: (2014)

Modeling Fragile X Syndrome in Drosophila
por: Drozd, Małgorzata, et al.
Publicado: (2018)

Chloride imbalance in Fragile X syndrome
por: Miles, Kaleb Dee, et al.
Publicado: (2022)

Distinctive behavioral and cellular responses to fluoxetine in the mouse model for Fragile X syndrome
por: Uutela, Marko, et al.
Publicado: (2014)

Interneuron Types and Their Circuits in the Basolateral Amygdala
por: Hájos, Norbert
Publicado: (2021)

Behavioral and Synaptic Circuit Features in a Zebrafish Model of Fragile X Syndrome
por: Ng, Ming-Chong, et al.
Publicado: (2013)

Hyperexcitability and Homeostasis in Fragile X Syndrome
por: Liu, Xiaopeng, et al.
Publicado: (2022)

An inhibitory circuit from central amygdala to zona incerta drives pain-related behaviors in mice
por: Singh, Sudhuman, et al.
Publicado: (2022)

Event-related potential alterations in fragile X syndrome
por: Knoth, Inga S., et al.
Publicado: (2012)

Fragile X Syndrome: Prevalence, Treatment, and Prevention in China
por: Niu, Manman, et al.
Publicado: (2017)

Deficient Sleep in Mouse Models of Fragile X Syndrome
por: Saré, R. Michelle, et al.
Publicado: (2017)

Neurodevelopment and early pharmacological interventions in Fragile X Syndrome
por: Milla, Luis A., et al.
Publicado: (2023)

Negative Effects of Chronic Rapamycin Treatment on Behavior in a Mouse Model of Fragile X Syndrome
por: Saré, Rachel M., et al.
Publicado: (2018)

Temporal Requirements of the Fragile X Mental Retardation Protein in Modulating Circadian Clock Circuit Synaptic Architecture
por: Gatto, Cheryl L., et al.
Publicado: (2009)

Impaired GABA Neural Circuits Are Critical for Fragile X Syndrome
por: Gao, Fei, et al.
Publicado: (2018)

Characterization of Auditory and Binaural Spatial Hearing in a Fragile X Syndrome Mouse Model
por: McCullagh, Elizabeth A., et al.
Publicado: (2020)

Integrated Behavioral, Genetic and Brain Circuit Visualization Methods to Unravel Functional Anatomy of Zebrafish Amygdala
por: Lal, Pradeep, et al.
Publicado: (2022)

Tripartite extended amygdala–basal ganglia CRH circuit drives locomotor activation and avoidance behavior
por: Chang, Simon, et al.
Publicado: (2022)

Inhibitory Circuits in the Basolateral Amygdala in Aversive Learning and Memory
por: Perumal, Madhusoothanan B., et al.
Publicado: (2021)

Cellular, circuit and transcriptional framework for modulation of itch in the central amygdala
por: Samineni, Vijay K, et al.
Publicado: (2021)

Dynamic Object Representations in Infants with and without Fragile X Syndrome
por: Farzin, Faraz, et al.
Publicado: (2010)

Reevaluation of FMR1 Hypermethylation Timing in Fragile X Syndrome
por: Mor-Shaked, Hagar, et al.
Publicado: (2018)

Auditory EEG Biomarkers in Fragile X Syndrome: Clinical Relevance
por: Ethridge, Lauren E., et al.
Publicado: (2019)

Visual Behavior Impairments as an Aberrant Sensory Processing in the Mouse Model of Fragile X Syndrome
por: Felgerolle, Chloé, et al.
Publicado: (2019)

Embryonic transcription factor expression in mice predicts medial amygdala neuronal identity and sex-specific responses to innate behavioral cues
por: Lischinsky, Julieta E, et al.
Publicado: (2017)

MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID, and Fragile X syndrome
por: Siew, Wei-Hong, et al.
Publicado: (2013)

Effects of Treatment With Hypnotics on Reduced Sleep Duration and Behavior Abnormalities in a Mouse Model of Fragile X Syndrome
por: Saré, Rachel Michelle, et al.
Publicado: (2022)

STDP and Mental Retardation: Dysregulation of Dendritic Excitability in Fragile X Syndrome
por: Meredith, Rhiannon M., et al.
Publicado: (2010)

The Search for an Effective Therapy to Treat Fragile X Syndrome: Dream or Reality?
por: Castagnola, Sara, et al.
Publicado: (2017)

Structural and Functional Abnormalities in the Olfactory System of Fragile X Syndrome Models
por: Bodaleo, Felipe, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_pc5am50rjf4mo329jvq60miuok