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Rates of phototherapy among ABO-incompatible newborns with a negative direct antiglobulin test

OBJECTIVE: We analyze phototherapy rates after implementation of a Hyperbilirubinemia Clinical Pathway (HCP), which placed full-term ABOi DAT negative newborns on the low risk phototherapy nomogram, rather than medium risk, as previously done. STUDY DESIGN: A chart review was performed for ABOi newb...

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Autores principales: Gabbay, Jonathan M., Agneta, Elizabeth M., Turkington, Simon, Bajaj, Benjamin M., Sinha, Bharati, Geha, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034253/
https://www.ncbi.nlm.nih.gov/pubmed/36959468
http://dx.doi.org/10.1038/s41372-023-01650-3
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author Gabbay, Jonathan M.
Agneta, Elizabeth M.
Turkington, Simon
Bajaj, Benjamin M.
Sinha, Bharati
Geha, Tanya
author_facet Gabbay, Jonathan M.
Agneta, Elizabeth M.
Turkington, Simon
Bajaj, Benjamin M.
Sinha, Bharati
Geha, Tanya
author_sort Gabbay, Jonathan M.
collection PubMed
description OBJECTIVE: We analyze phototherapy rates after implementation of a Hyperbilirubinemia Clinical Pathway (HCP), which placed full-term ABOi DAT negative newborns on the low risk phototherapy nomogram, rather than medium risk, as previously done. STUDY DESIGN: A chart review was performed for ABOi newborns born ≥36 weeks gestation between January 2020 and October 2021. Primary outcome measures were rates of phototherapy across pre- and post-intervention groups and among DAT negative newborns. RESULTS: There was an increased proportion of newborns assigned to the low risk curve after the intervention. There were no significant differences in phototherapy rates among the intervention groups, although there was a non-significant decrease in phototherapy rates among DAT negative newborns after the intervention. There were no increases in adverse outcomes. CONCLUSIONS: Providers adhered to the guidelines after implementation of the HCP. ABOi DAT negative newborns can be viewed as low risk for hyperbilirubinemia requiring phototherapy.
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spelling pubmed-100342532023-03-23 Rates of phototherapy among ABO-incompatible newborns with a negative direct antiglobulin test Gabbay, Jonathan M. Agneta, Elizabeth M. Turkington, Simon Bajaj, Benjamin M. Sinha, Bharati Geha, Tanya J Perinatol Article OBJECTIVE: We analyze phototherapy rates after implementation of a Hyperbilirubinemia Clinical Pathway (HCP), which placed full-term ABOi DAT negative newborns on the low risk phototherapy nomogram, rather than medium risk, as previously done. STUDY DESIGN: A chart review was performed for ABOi newborns born ≥36 weeks gestation between January 2020 and October 2021. Primary outcome measures were rates of phototherapy across pre- and post-intervention groups and among DAT negative newborns. RESULTS: There was an increased proportion of newborns assigned to the low risk curve after the intervention. There were no significant differences in phototherapy rates among the intervention groups, although there was a non-significant decrease in phototherapy rates among DAT negative newborns after the intervention. There were no increases in adverse outcomes. CONCLUSIONS: Providers adhered to the guidelines after implementation of the HCP. ABOi DAT negative newborns can be viewed as low risk for hyperbilirubinemia requiring phototherapy. Nature Publishing Group US 2023-03-23 /pmc/articles/PMC10034253/ /pubmed/36959468 http://dx.doi.org/10.1038/s41372-023-01650-3 Text en © The Author(s), under exclusive licence to Springer Nature America, Inc. 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Gabbay, Jonathan M.
Agneta, Elizabeth M.
Turkington, Simon
Bajaj, Benjamin M.
Sinha, Bharati
Geha, Tanya
Rates of phototherapy among ABO-incompatible newborns with a negative direct antiglobulin test
title Rates of phototherapy among ABO-incompatible newborns with a negative direct antiglobulin test
title_full Rates of phototherapy among ABO-incompatible newborns with a negative direct antiglobulin test
title_fullStr Rates of phototherapy among ABO-incompatible newborns with a negative direct antiglobulin test
title_full_unstemmed Rates of phototherapy among ABO-incompatible newborns with a negative direct antiglobulin test
title_short Rates of phototherapy among ABO-incompatible newborns with a negative direct antiglobulin test
title_sort rates of phototherapy among abo-incompatible newborns with a negative direct antiglobulin test
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034253/
https://www.ncbi.nlm.nih.gov/pubmed/36959468
http://dx.doi.org/10.1038/s41372-023-01650-3
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