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Targeting TGF-β1/miR-21 Pathway in Keratinocytes Reveals Protective Effects of Silymarin on Imiquimod-Induced Psoriasis Mouse Model

Epidermal cells integrate multiple signals that activate the signaling pathways involved in skin homeostasis. TGF-β1 signaling pathway upregulates microRNA (miR)-21-5p in keratinocytes and is often deregulated in skin diseases. To identify the bioactive compounds that enable to modulate the TGF-β1/m...

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Detalles Bibliográficos
Autores principales:	Henriet, Elodie, Abdallah, Florence, Laurent, Yoan, Guimpied, Cyril, Clement, Emily, Simon, Michel, Pichon, Chantal, Baril, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034514/ https://www.ncbi.nlm.nih.gov/pubmed/36968096 http://dx.doi.org/10.1016/j.xjidi.2022.100175

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