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Blockade of neutrophil recruitment to tumor sites based on sialic acid-modified nanoplatforms enhances the efficacy of checkpoint blockade immunotherapy

Checkpoint inhibitors are designed to rejuvenate depleted or suppressed T cells in the tumor microenvironment, relying on the immune system to control and kill tumors. However, accumulating evidence indicates that tumor-infiltrating neutrophils impede the proliferation and activation of T cells and...

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Detalles Bibliográficos
Autores principales: Chen, Meng, Qi, Zhaowei, Meng, Xianmin, Wang, Shuo, Zheng, Xueying, Hu, Miao, Liu, Xinrong, Song, Yanzhi, Deng, Yihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034569/
https://www.ncbi.nlm.nih.gov/pubmed/36968653
http://dx.doi.org/10.1016/j.ajps.2023.100784