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Using Peptide Nucleic Acid Hybridization Probes for Qualitative and Quantitative Analysis of Nucleic Acid Therapeutics by Capillary Electrophoresis
[Image: see text] The space of advanced therapeutic modalities is currently evolving in rapid pace necessitating continuous improvement of analytical quality control methods. In order to evaluate the identity of nucleic acid species in gene therapy products, we propose a capillary electrophoresis-ba...
Autores principales: | Hutanu, Andrei, Signori, Chiara, Moritz, Bernd, Gregoritza, Manuel, Rohde, Adelheid, Schwarz, Maria A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034743/ https://www.ncbi.nlm.nih.gov/pubmed/36888566 http://dx.doi.org/10.1021/acs.analchem.2c04813 |
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