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Using Peptide Nucleic Acid Hybridization Probes for Qualitative and Quantitative Analysis of Nucleic Acid Therapeutics by Capillary Electrophoresis

[Image: see text] The space of advanced therapeutic modalities is currently evolving in rapid pace necessitating continuous improvement of analytical quality control methods. In order to evaluate the identity of nucleic acid species in gene therapy products, we propose a capillary electrophoresis-ba...

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Detalles Bibliográficos
Autores principales: Hutanu, Andrei, Signori, Chiara, Moritz, Bernd, Gregoritza, Manuel, Rohde, Adelheid, Schwarz, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034743/
https://www.ncbi.nlm.nih.gov/pubmed/36888566
http://dx.doi.org/10.1021/acs.analchem.2c04813

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