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Recent advances in perioperative blood management

Transfusion of blood and blood products has many adverse effects and should be done only if patient benefits outweigh the associated risks. Current understanding of blood transfusion has improved dramatically, revolutionising the care of surgical, trauma, obstetric and critically ill patients. Most...

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Autores principales: Krishna, Handattu M., Prasad, Mukesh Kumar, Mitragotri, Milon V., Bipin, G. I, Gupta, Divya, Sharma, Ridhima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034933/
https://www.ncbi.nlm.nih.gov/pubmed/36970482
http://dx.doi.org/10.4103/ija.ija_1043_22
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author Krishna, Handattu M.
Prasad, Mukesh Kumar
Mitragotri, Milon V.
Bipin, G. I
Gupta, Divya
Sharma, Ridhima
author_facet Krishna, Handattu M.
Prasad, Mukesh Kumar
Mitragotri, Milon V.
Bipin, G. I
Gupta, Divya
Sharma, Ridhima
author_sort Krishna, Handattu M.
collection PubMed
description Transfusion of blood and blood products has many adverse effects and should be done only if patient benefits outweigh the associated risks. Current understanding of blood transfusion has improved dramatically, revolutionising the care of surgical, trauma, obstetric and critically ill patients. Most guidelines advise a restrictive approach for stable patients with non-haemorrhagic anaemia for red blood cell transfusion. The rationale for red blood cell transfusion has historically been to improve oxygen transport capacity and consumption-related parameters in anaemic patients. Current understanding casts serious doubts about the true potential of red blood cell transfusions to improve these factors. There may not be any benefit from blood transfusion beyond a haemoglobin threshold of 7 g/dL. In fact, liberal transfusion may be associated with higher complications. Guideline-based transfusion policy should be adopted for the administration of all blood products including fresh frozen plasma, platelet concentrates and cryoprecipitate etc. This should be integrated with clinical judgement.
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spelling pubmed-100349332023-03-24 Recent advances in perioperative blood management Krishna, Handattu M. Prasad, Mukesh Kumar Mitragotri, Milon V. Bipin, G. I Gupta, Divya Sharma, Ridhima Indian J Anaesth Special Article Transfusion of blood and blood products has many adverse effects and should be done only if patient benefits outweigh the associated risks. Current understanding of blood transfusion has improved dramatically, revolutionising the care of surgical, trauma, obstetric and critically ill patients. Most guidelines advise a restrictive approach for stable patients with non-haemorrhagic anaemia for red blood cell transfusion. The rationale for red blood cell transfusion has historically been to improve oxygen transport capacity and consumption-related parameters in anaemic patients. Current understanding casts serious doubts about the true potential of red blood cell transfusions to improve these factors. There may not be any benefit from blood transfusion beyond a haemoglobin threshold of 7 g/dL. In fact, liberal transfusion may be associated with higher complications. Guideline-based transfusion policy should be adopted for the administration of all blood products including fresh frozen plasma, platelet concentrates and cryoprecipitate etc. This should be integrated with clinical judgement. Wolters Kluwer - Medknow 2023-01 2023-01-21 /pmc/articles/PMC10034933/ /pubmed/36970482 http://dx.doi.org/10.4103/ija.ija_1043_22 Text en Copyright: © 2023 Indian Journal of Anaesthesia https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Special Article
Krishna, Handattu M.
Prasad, Mukesh Kumar
Mitragotri, Milon V.
Bipin, G. I
Gupta, Divya
Sharma, Ridhima
Recent advances in perioperative blood management
title Recent advances in perioperative blood management
title_full Recent advances in perioperative blood management
title_fullStr Recent advances in perioperative blood management
title_full_unstemmed Recent advances in perioperative blood management
title_short Recent advances in perioperative blood management
title_sort recent advances in perioperative blood management
topic Special Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10034933/
https://www.ncbi.nlm.nih.gov/pubmed/36970482
http://dx.doi.org/10.4103/ija.ija_1043_22
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