DNA G-Quadruplex-Binding Protein Developed Using the RGG Domain of Translocated in Liposarcoma/Fused in Sarcoma Inhibits Transcription of bcl-2

[Image: see text] The G-quadruplexes (G4s) in the genome are important drug targets because they regulate gene expression and the genome structure. Several small molecules that bind the G4 have been developed, but few artificial G4 binding proteins have been reported. We previously reported a novel...

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Detalles Bibliográficos
Autores principales: Ulum, Luthfi Lulul, Karikome, Yamato, Yagi, Ryota, Kawashima, Tomoe, Ishihara, Akinori, Oyoshi, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035022/
https://www.ncbi.nlm.nih.gov/pubmed/36969440
http://dx.doi.org/10.1021/acsomega.3c00050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035022/
https://www.ncbi.nlm.nih.gov/pubmed/36969440
http://dx.doi.org/10.1021/acsomega.3c00050

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