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Modified Palomo Procedure Is an Effective Intervention for Improving Serum Testosterone Levels and Semen Parameters in Patients With Varicocele: A Prospective Study

Background: A varicocele can be defined as an abnormal venous dilatation and/or tortuosity of the pampiniform plexus. It is generally reported that varicoceles are present in 15% of the general male population and 35% of men as a cause of primary infertility and in up to 80% of men as a cause of sec...

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Autores principales: Kalwaniya, Dheer S, Tolat, Aditya, Kumar, Devender, Naga Rohith, Vakulabharanam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035055/
https://www.ncbi.nlm.nih.gov/pubmed/36968902
http://dx.doi.org/10.7759/cureus.35252
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author Kalwaniya, Dheer S
Tolat, Aditya
Kumar, Devender
Naga Rohith, Vakulabharanam
author_facet Kalwaniya, Dheer S
Tolat, Aditya
Kumar, Devender
Naga Rohith, Vakulabharanam
author_sort Kalwaniya, Dheer S
collection PubMed
description Background: A varicocele can be defined as an abnormal venous dilatation and/or tortuosity of the pampiniform plexus. It is generally reported that varicoceles are present in 15% of the general male population and 35% of men as a cause of primary infertility and in up to 80% of men as a cause of secondary infertility. Differences in venous drainage anatomy between the left and right internal spermatic veins, venous valve incompetence resulting in venous blood reflux, and increased hydrostatic pressure are the most commonly cited theories. Various surgical and non-surgical techniques are in use for treating patients with varicocele. Here we used a modified Palamo procedure to treat the patients and observed the outcome. Methodology: A total of 40 patients with varicocele were recruited for the study. A preoperative evaluation, along with serum testosterone levels and semen analysis, was done. A modified Palomo technique was used to treat varicocele. A postoperative follow-up with serum testosterone levels and semen analysis was done to observe improvement. Results: The mean (±SD) left testis size, right testis size, testosterone, sperm concentration, sperm vitality and sperm progressive motility were found statistically significantly higher in patients after surgery as compared to patients before surgery (p<0.05). However, there was statistically insignificant mean difference in semen volume between patients before surgery and patients after surgery (p>0.05). Conclusion: Modified Palomo procedure can be used to treat varicocele with good improvement in serum testosterone levels and semen parameters.
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spelling pubmed-100350552023-03-24 Modified Palomo Procedure Is an Effective Intervention for Improving Serum Testosterone Levels and Semen Parameters in Patients With Varicocele: A Prospective Study Kalwaniya, Dheer S Tolat, Aditya Kumar, Devender Naga Rohith, Vakulabharanam Cureus Pathology Background: A varicocele can be defined as an abnormal venous dilatation and/or tortuosity of the pampiniform plexus. It is generally reported that varicoceles are present in 15% of the general male population and 35% of men as a cause of primary infertility and in up to 80% of men as a cause of secondary infertility. Differences in venous drainage anatomy between the left and right internal spermatic veins, venous valve incompetence resulting in venous blood reflux, and increased hydrostatic pressure are the most commonly cited theories. Various surgical and non-surgical techniques are in use for treating patients with varicocele. Here we used a modified Palamo procedure to treat the patients and observed the outcome. Methodology: A total of 40 patients with varicocele were recruited for the study. A preoperative evaluation, along with serum testosterone levels and semen analysis, was done. A modified Palomo technique was used to treat varicocele. A postoperative follow-up with serum testosterone levels and semen analysis was done to observe improvement. Results: The mean (±SD) left testis size, right testis size, testosterone, sperm concentration, sperm vitality and sperm progressive motility were found statistically significantly higher in patients after surgery as compared to patients before surgery (p<0.05). However, there was statistically insignificant mean difference in semen volume between patients before surgery and patients after surgery (p>0.05). Conclusion: Modified Palomo procedure can be used to treat varicocele with good improvement in serum testosterone levels and semen parameters. Cureus 2023-02-21 /pmc/articles/PMC10035055/ /pubmed/36968902 http://dx.doi.org/10.7759/cureus.35252 Text en Copyright © 2023, Kalwaniya et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Kalwaniya, Dheer S
Tolat, Aditya
Kumar, Devender
Naga Rohith, Vakulabharanam
Modified Palomo Procedure Is an Effective Intervention for Improving Serum Testosterone Levels and Semen Parameters in Patients With Varicocele: A Prospective Study
title Modified Palomo Procedure Is an Effective Intervention for Improving Serum Testosterone Levels and Semen Parameters in Patients With Varicocele: A Prospective Study
title_full Modified Palomo Procedure Is an Effective Intervention for Improving Serum Testosterone Levels and Semen Parameters in Patients With Varicocele: A Prospective Study
title_fullStr Modified Palomo Procedure Is an Effective Intervention for Improving Serum Testosterone Levels and Semen Parameters in Patients With Varicocele: A Prospective Study
title_full_unstemmed Modified Palomo Procedure Is an Effective Intervention for Improving Serum Testosterone Levels and Semen Parameters in Patients With Varicocele: A Prospective Study
title_short Modified Palomo Procedure Is an Effective Intervention for Improving Serum Testosterone Levels and Semen Parameters in Patients With Varicocele: A Prospective Study
title_sort modified palomo procedure is an effective intervention for improving serum testosterone levels and semen parameters in patients with varicocele: a prospective study
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035055/
https://www.ncbi.nlm.nih.gov/pubmed/36968902
http://dx.doi.org/10.7759/cureus.35252
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