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Exploiting butyrylcholinesterase inhibitors through a combined 3-D pharmacophore modeling, QSAR, molecular docking, and molecular dynamics investigation

Alzheimer's disease (AD), a neurodegenerative condition associated with ageing, can occur. AD gradually impairs memory and cognitive function, which leads to abnormal behavior, incapacity, and reliance. By 2050, there will likely be 100 million cases of AD in the world's population. Acetyl...

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Detalles Bibliográficos
Autores principales:	Kumar, Sunil, Manoharan, Amritha, J, Jayalakshmi, Abdelgawad, Mohamed A., Mahdi, Wael A., Alshehri, Sultan, Ghoneim, Mohammed M., Pappachen, Leena K., Zachariah, Subin Mary, Aneesh, T. P., Mathew, Bijo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035067/ https://www.ncbi.nlm.nih.gov/pubmed/36968055 http://dx.doi.org/10.1039/d3ra00526g

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