A retrospective analysis of conditional power assumptions in clinical trials with continuous or binary endpoints

BACKGROUND: Adaptive clinical trials may use conditional power (CP) to make decisions at interim analyses, requiring assumptions about the treatment effect for remaining patients. It is critical that these assumptions are understood by those using CP in decision-making, as well as timings of these d...

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Detalles Bibliográficos
Autores principales: Edwards, Julia M., Walters, Stephen J., Julious, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035140/
https://www.ncbi.nlm.nih.gov/pubmed/36949524
http://dx.doi.org/10.1186/s13063-023-07202-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035140/
https://www.ncbi.nlm.nih.gov/pubmed/36949524
http://dx.doi.org/10.1186/s13063-023-07202-6

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