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Clusters of co-abundant proteins in the brain cortex associated with fronto-temporal lobar degeneration

BACKGROUND: Frontotemporal lobar degeneration (FTLD) is characterized pathologically by neuronal and glial inclusions of hyperphosphorylated tau or by neuronal cytoplasmic inclusions of TDP43. This study aimed at deciphering the molecular mechanisms leading to these distinct pathological subtypes. M...

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Detalles Bibliográficos
Autores principales: Bridel, Claire, van Gils, Juami H. M., Miedema, Suzanne S. M., Hoozemans, Jeroen J. M., Pijnenburg, Yolande A. L., Smit, August B., Rozemuller, Annemieke J. M., Abeln, Sanne, Teunissen, Charlotte E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035199/
https://www.ncbi.nlm.nih.gov/pubmed/36949537
http://dx.doi.org/10.1186/s13195-023-01200-1