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A Phase II Study Investigating Cabozantinib in Patients with Refractory Metastatic Colorectal Cancer (AGICC 17CRC01)
PURPOSE: Multi-tyrosine kinase inhibitors (TKI) have shown clinical activity in patients with metastatic colorectal cancer. Cabozantinib, a multi-TKI, exhibited potent antitumor activity superior to regorafenib in preclinical colorectal cancer patient-derived tumor xenograft models. This phase II st...
Autores principales: | Scott, Aaron J., Basu Mallick, Atrayee, Dotan, Efrat, Cohen, Steven J., Gold, Philip J., Hochster, Howard S., Subramaniam, Somasundaram, Barzi, Afsaneh, Watts, George S., Blatchford, Patrick J., Messersmith, Wells A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035393/ https://www.ncbi.nlm.nih.gov/pubmed/36969746 http://dx.doi.org/10.1158/2767-9764.CRC-22-0169 |
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