CD47-blocking Antibody ZL-1201 Promotes Tumor-associated Macrophage Phagocytic Activity and Enhances the Efficacy of the Therapeutic Antibodies and Chemotherapy

Tumor-associated macrophages (TAM) are the most abundant immune cells in the tumor microenvironment. They consist of various subsets but primarily resemble the M2 macrophage phenotype. TAMs are known to promote tumor progression and are associated with poor clinical outcomes. CD47 on tumor cells and...

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Detalles Bibliográficos
Autores principales: Cao, Anthony, Yi, Jiaqing, Tang, Xinyan, Szeto, Christopher W., Wu, Renyi, Wan, Bing, Fang, Xu, Li, Shou, Wang, Lei, Wang, Lina, Li, Jing, Ye, Qiuping, Huang, Tom, Hsu, Karl, Kabbarah, Omar, Zhou, Haiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035405/
https://www.ncbi.nlm.nih.gov/pubmed/36970051
http://dx.doi.org/10.1158/2767-9764.CRC-22-0266

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