License to kill: Retinoic acid programs T cells for tissue residency

In this issue of JEM, Qiu et al. (2023. J. Exp. Med. https://doi.org/10.1084/jem.20210923) show that retinoic acid signaling during priming in the mesenteric lymph node licenses CD8(+) T cells to develop into small intestinal tissue-resident memory cells, a finding that provides key insights into ti...

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Detalles Bibliográficos
Autores principales: Heeg, Maximilian, Goldrath, Ananda W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Insights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035436/
https://www.ncbi.nlm.nih.gov/pubmed/36897330
http://dx.doi.org/10.1084/jem.20230161
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author Heeg, Maximilian
Goldrath, Ananda W.
author_facet Heeg, Maximilian
Goldrath, Ananda W.
author_sort Heeg, Maximilian
collection PubMed
description In this issue of JEM, Qiu et al. (2023. J. Exp. Med. https://doi.org/10.1084/jem.20210923) show that retinoic acid signaling during priming in the mesenteric lymph node licenses CD8(+) T cells to develop into small intestinal tissue-resident memory cells, a finding that provides key insights into tissue-specific vaccination strategies.
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spelling pubmed-100354362023-09-10 License to kill: Retinoic acid programs T cells for tissue residency Heeg, Maximilian Goldrath, Ananda W. J Exp Med Insights In this issue of JEM, Qiu et al. (2023. J. Exp. Med. https://doi.org/10.1084/jem.20210923) show that retinoic acid signaling during priming in the mesenteric lymph node licenses CD8(+) T cells to develop into small intestinal tissue-resident memory cells, a finding that provides key insights into tissue-specific vaccination strategies. Rockefeller University Press 2023-03-10 /pmc/articles/PMC10035436/ /pubmed/36897330 http://dx.doi.org/10.1084/jem.20230161 Text en © 2023 Heeg and Goldrath https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Insights
Heeg, Maximilian
Goldrath, Ananda W.
License to kill: Retinoic acid programs T cells for tissue residency
title License to kill: Retinoic acid programs T cells for tissue residency
title_full License to kill: Retinoic acid programs T cells for tissue residency
title_fullStr License to kill: Retinoic acid programs T cells for tissue residency
title_full_unstemmed License to kill: Retinoic acid programs T cells for tissue residency
title_short License to kill: Retinoic acid programs T cells for tissue residency
title_sort license to kill: retinoic acid programs t cells for tissue residency
topic Insights
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035436/
https://www.ncbi.nlm.nih.gov/pubmed/36897330
http://dx.doi.org/10.1084/jem.20230161
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