Cargando…

On the Choice of Longitudinal Models for the Analysis of Antitumor Efficacy in Mouse Clinical Trials of Patient-derived Xenograft Models

In translational oncology research, the patient-derived xenograft (PDX) model and its use in mouse clinical trials (MCT) are increasingly described. This involves transplanting a human tumor into a mouse and studying its evolution during follow-up or until death. A MCT contains several PDXs in which...

Descripción completa

Detalles Bibliográficos
Autores principales: Savel, Hélène, Barbier, Sandrine, Proust-Lima, Cécile, Rondeau, Virginie, Thiébaut, Rodolphe, Meyer-Losic, Florence, Richert, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035449/
https://www.ncbi.nlm.nih.gov/pubmed/36968232
http://dx.doi.org/10.1158/2767-9764.CRC-22-0238