Misaligned Chromosomes are a Major Source of Chromosomal Instability in Breast Cancer

Chromosomal instability (CIN), the persistent reshuffling of chromosomes during mitosis, is a hallmark of human cancers that contributes to tumor heterogeneity and has been implicated in driving metastasis and altering responses to therapy. Though multiple mechanisms can produce CIN, lagging chromos...

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Detalles Bibliográficos
Autores principales: Tucker, John B., Bonema, Sarah C., García-Varela, Rebeca, Denu, Ryan A., Hu, Yang, McGregor, Stephanie M., Burkard, Mark E., Weaver, Beth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035514/
https://www.ncbi.nlm.nih.gov/pubmed/36968230
http://dx.doi.org/10.1158/2767-9764.CRC-22-0302

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