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A Phase I Trial of VEGF-A Inhibition Combined with PD-L1 Blockade for Recurrent Glioblastoma

PURPOSE: The treatment of glioblastoma (GBM) poses challenges. The use of immune checkpoint inhibition (ICI) has been disappointing as GBM is characterized by low mutational burden and low T-cell infiltration. The combination of ICI with other treatment modalities may improve efficacy. PATIENT AND M...

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Detalles Bibliográficos
Autores principales:	Chiu, Daniel, Qi, Jingjing, Thin, Tin Htwe, Garcia-Barros, Monica, Lee, Brian, Hahn, Mary, Mandeli, John, Belani, Puneet, Nael, Kambiz, Rashidipour, Omid, Ghatan, Saadi, Hadjipanayis, Constantinos G., Yong, Raymund L., Germano, Isabelle M., Brody, Rachel, Tsankova, Nadejda M., Gnjatic, Sacha, Kim-Schulze, Seunghee, Hormigo, Adília
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035521/ https://www.ncbi.nlm.nih.gov/pubmed/36968223 http://dx.doi.org/10.1158/2767-9764.CRC-22-0420

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