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Spatial mapping reveals granuloma diversity and histopathological superstructure in human tuberculosis
The hallmark of tuberculosis (TB) is the formation of immune cell-enriched aggregates called granulomas. While granulomas are pathologically diverse, their tissue-wide heterogeneity has not been spatially resolved at the single-cell level in human tissues. By spatially mapping individual immune cell...
Autores principales: | Sawyer, Andrew J., Patrick, Ellis, Edwards, Jarem, Wilmott, James S., Fielder, Timothy, Yang, Qianting, Barber, Daniel L., Ernst, Joel D., Britton, Warwick J., Palendira, Umaimainthan, Chen, Xinchun, Feng, Carl G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035589/ https://www.ncbi.nlm.nih.gov/pubmed/36920308 http://dx.doi.org/10.1084/jem.20221392 |
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