Metastatic Renal Cell Carcinoma and Unforeseen Adrenal Insufficiency: A Case Report and Literature Review

Renal cell carcinoma (RCC) can metastasize to nearly every organ, yet rarely metastasizes to the adrenal glands despite their anatomical proximity. Adrenal metastases are typically incidental findings on medical imaging and are vastly clinically asymptomatic. The adrenal glands can maintain hormonal...

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Detalles Bibliográficos
Autores principales: Repp, Matthew L, Alvarez, Rodrigo A, Arevalo-Salazar, Dory E, Kotagiri, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035604/
https://www.ncbi.nlm.nih.gov/pubmed/36968872
http://dx.doi.org/10.7759/cureus.35265
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author Repp, Matthew L
Alvarez, Rodrigo A
Arevalo-Salazar, Dory E
Kotagiri, Rajesh
author_facet Repp, Matthew L
Alvarez, Rodrigo A
Arevalo-Salazar, Dory E
Kotagiri, Rajesh
author_sort Repp, Matthew L
collection PubMed
description Renal cell carcinoma (RCC) can metastasize to nearly every organ, yet rarely metastasizes to the adrenal glands despite their anatomical proximity. Adrenal metastases are typically incidental findings on medical imaging and are vastly clinically asymptomatic. The adrenal glands can maintain hormonal homeostasis if a tenth of total adrenal gland function is preserved. We present a patient with synchronous bilateral adrenal metastases from RCC with rapid and unexpected development of adrenal insufficiency (AI).
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spelling pubmed-100356042023-03-24 Metastatic Renal Cell Carcinoma and Unforeseen Adrenal Insufficiency: A Case Report and Literature Review Repp, Matthew L Alvarez, Rodrigo A Arevalo-Salazar, Dory E Kotagiri, Rajesh Cureus Pathology Renal cell carcinoma (RCC) can metastasize to nearly every organ, yet rarely metastasizes to the adrenal glands despite their anatomical proximity. Adrenal metastases are typically incidental findings on medical imaging and are vastly clinically asymptomatic. The adrenal glands can maintain hormonal homeostasis if a tenth of total adrenal gland function is preserved. We present a patient with synchronous bilateral adrenal metastases from RCC with rapid and unexpected development of adrenal insufficiency (AI). Cureus 2023-02-21 /pmc/articles/PMC10035604/ /pubmed/36968872 http://dx.doi.org/10.7759/cureus.35265 Text en Copyright © 2023, Repp et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Repp, Matthew L
Alvarez, Rodrigo A
Arevalo-Salazar, Dory E
Kotagiri, Rajesh
Metastatic Renal Cell Carcinoma and Unforeseen Adrenal Insufficiency: A Case Report and Literature Review
title Metastatic Renal Cell Carcinoma and Unforeseen Adrenal Insufficiency: A Case Report and Literature Review
title_full Metastatic Renal Cell Carcinoma and Unforeseen Adrenal Insufficiency: A Case Report and Literature Review
title_fullStr Metastatic Renal Cell Carcinoma and Unforeseen Adrenal Insufficiency: A Case Report and Literature Review
title_full_unstemmed Metastatic Renal Cell Carcinoma and Unforeseen Adrenal Insufficiency: A Case Report and Literature Review
title_short Metastatic Renal Cell Carcinoma and Unforeseen Adrenal Insufficiency: A Case Report and Literature Review
title_sort metastatic renal cell carcinoma and unforeseen adrenal insufficiency: a case report and literature review
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035604/
https://www.ncbi.nlm.nih.gov/pubmed/36968872
http://dx.doi.org/10.7759/cureus.35265
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