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Histopathological Variants of Hepatocellular Carcinomas: an Update According to the 5th Edition of the WHO Classification of Digestive System Tumors
Hepatocellular carcinoma (HCC) is heterogeneous in pathogenesis, phenotype and biological behavior. Various histopathological features of HCC had been sporadically described, and with the identification of common molecular alterations of HCC and its genomic landscape over the last decade, morpho-mol...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Korean Liver Cancer Association
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035696/ https://www.ncbi.nlm.nih.gov/pubmed/37383050 http://dx.doi.org/10.17998/jlc.20.1.17 |
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author | Kim, Haeryoung Jang, Mi Park, Young Nyun |
author_facet | Kim, Haeryoung Jang, Mi Park, Young Nyun |
author_sort | Kim, Haeryoung |
collection | PubMed |
description | Hepatocellular carcinoma (HCC) is heterogeneous in pathogenesis, phenotype and biological behavior. Various histopathological features of HCC had been sporadically described, and with the identification of common molecular alterations of HCC and its genomic landscape over the last decade, morpho-molecular correlation of HCC has become possible. As a result, up to 35% of HCCs can now be classified into histopathological variants, many of which have unique molecular characteristics. This review will provide an introduction to the variously described histopathological variants of HCC in the updated WHO Classification of Digestive System Tumors. |
format | Online Article Text |
id | pubmed-10035696 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Korean Liver Cancer Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-100356962023-06-28 Histopathological Variants of Hepatocellular Carcinomas: an Update According to the 5th Edition of the WHO Classification of Digestive System Tumors Kim, Haeryoung Jang, Mi Park, Young Nyun J Liver Cancer Review Article Hepatocellular carcinoma (HCC) is heterogeneous in pathogenesis, phenotype and biological behavior. Various histopathological features of HCC had been sporadically described, and with the identification of common molecular alterations of HCC and its genomic landscape over the last decade, morpho-molecular correlation of HCC has become possible. As a result, up to 35% of HCCs can now be classified into histopathological variants, many of which have unique molecular characteristics. This review will provide an introduction to the variously described histopathological variants of HCC in the updated WHO Classification of Digestive System Tumors. The Korean Liver Cancer Association 2020-03 2020-03-31 /pmc/articles/PMC10035696/ /pubmed/37383050 http://dx.doi.org/10.17998/jlc.20.1.17 Text en Copyright © 2020 The Korean Liver Cancer Association https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Kim, Haeryoung Jang, Mi Park, Young Nyun Histopathological Variants of Hepatocellular Carcinomas: an Update According to the 5th Edition of the WHO Classification of Digestive System Tumors |
title | Histopathological Variants of Hepatocellular Carcinomas: an Update According to the 5th Edition of the WHO Classification of Digestive System Tumors |
title_full | Histopathological Variants of Hepatocellular Carcinomas: an Update According to the 5th Edition of the WHO Classification of Digestive System Tumors |
title_fullStr | Histopathological Variants of Hepatocellular Carcinomas: an Update According to the 5th Edition of the WHO Classification of Digestive System Tumors |
title_full_unstemmed | Histopathological Variants of Hepatocellular Carcinomas: an Update According to the 5th Edition of the WHO Classification of Digestive System Tumors |
title_short | Histopathological Variants of Hepatocellular Carcinomas: an Update According to the 5th Edition of the WHO Classification of Digestive System Tumors |
title_sort | histopathological variants of hepatocellular carcinomas: an update according to the 5th edition of the who classification of digestive system tumors |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035696/ https://www.ncbi.nlm.nih.gov/pubmed/37383050 http://dx.doi.org/10.17998/jlc.20.1.17 |
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