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Primate protein-ligand interfaces exhibit significant conservation and unveil human-specific evolutionary drivers

Despite the vast phenotypic differences observed across primates, their protein products are largely similar to each other at the sequence level. We hypothesized that, since proteins accomplish all their functions via interactions with other molecules, alterations in the sites that participate in th...

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Detalles Bibliográficos
Autores principales: King, Sean B., Singh, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035887/
https://www.ncbi.nlm.nih.gov/pubmed/36952575
http://dx.doi.org/10.1371/journal.pcbi.1010966

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