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First passage time analysis of spatial mutation patterns reveals sub-clonal evolutionary dynamics in colorectal cancer
The signature of early cancer dynamics on the spatial arrangement of tumour cells is poorly understood, and yet could encode information about how sub-clones grew within the expanding tumour. Novel methods of quantifying spatial tumour data at the cellular scale are required to link evolutionary dyn...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10035892/ https://www.ncbi.nlm.nih.gov/pubmed/36913406 http://dx.doi.org/10.1371/journal.pcbi.1010952 |