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UCHL3 promotes hepatocellular carcinoma cell migration by de-ubiquitinating and stabilizing Vimentin

BACKGROUND: Hepatocellular carcinoma (HCC) is a common malignant tumor associated with a poor prognosis. Ubiquitin carboxyl-terminal hydrolase L3 (UCHL3) has been reported to promote diverse tumors, but little is known about its role in HCC. METHODS: Expression levels of UCHL3 in Huh7 and Hep3B cell...

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Detalles Bibliográficos
Autores principales: Ma, Qiancheng, Lu, Qiliang, Lei, Xiangxiang, Zhao, Jie, Sun, Wen, Wang, Jun, Zhu, Qing, Huang, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036040/
https://www.ncbi.nlm.nih.gov/pubmed/36969045
http://dx.doi.org/10.3389/fonc.2023.1088475