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Structural basis for the Rad6 activation by the Bre1 N-terminal domain

The mono-ubiquitination of the histone protein H2B (H2Bub1) is a highly conserved histone post-translational modification that plays critical roles in many fundamental processes. In yeast, this modification is catalyzed by the conserved Bre1–Rad6 complex. Bre1 contains a unique N-terminal Rad6-bindi...

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Detalles Bibliográficos
Autores principales: Shi, Meng, Zhao, Jiaqi, Zhang, Simin, Huang, Wei, Li, Mengfei, Bai, Xue, Zhang, Wenxue, Zhang, Kai, Chen, Xuefeng, Xiang, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036116/
https://www.ncbi.nlm.nih.gov/pubmed/36912886
http://dx.doi.org/10.7554/eLife.84157