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End to End Multitask Joint Learning Model for Osteoporosis Classification in CT Images

Osteoporosis is a significant global health concern that can be difficult to detect early due to a lack of symptoms. At present, the examination of osteoporosis depends mainly on methods containing dual-energyX-ray, quantitative CT, etc., which are high costs in terms of equipment and human time. Th...

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Autores principales: Zhang, Kun, Lin, Pengcheng, Pan, Jing, Xu, Peixia, Qiu, Xuechen, Crookes, Danny, Hua, Liang, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036193/
https://www.ncbi.nlm.nih.gov/pubmed/36970245
http://dx.doi.org/10.1155/2023/3018320
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author Zhang, Kun
Lin, Pengcheng
Pan, Jing
Xu, Peixia
Qiu, Xuechen
Crookes, Danny
Hua, Liang
Wang, Lin
author_facet Zhang, Kun
Lin, Pengcheng
Pan, Jing
Xu, Peixia
Qiu, Xuechen
Crookes, Danny
Hua, Liang
Wang, Lin
author_sort Zhang, Kun
collection PubMed
description Osteoporosis is a significant global health concern that can be difficult to detect early due to a lack of symptoms. At present, the examination of osteoporosis depends mainly on methods containing dual-energyX-ray, quantitative CT, etc., which are high costs in terms of equipment and human time. Therefore, a more efficient and economical method is urgently needed for diagnosing osteoporosis. With the development of deep learning, automatic diagnosis models for various diseases have been proposed. However, the establishment of these models generally requires images with only lesion areas, and annotating the lesion areas is time-consuming. To address this challenge, we propose a joint learning framework for osteoporosis diagnosis that combines localization, segmentation, and classification to enhance diagnostic accuracy. Our method includes a boundary heat map regression branch for thinning segmentation and a gated convolution module for adjusting context features in the classification module. We also integrate segmentation and classification features and propose a feature fusion module to adjust the weight of different levels of vertebrae. We trained our model on a self-built dataset and achieved an overall accuracy rate of 93.3% for the three label categories (normal, osteopenia, and osteoporosis) in the testing datasets. The area under the curve for the normal category is 0.973; for the osteopenia category, it is 0.965; and for the osteoporosis category, it is 0.985. Our method provides a promising alternative for the diagnosis of osteoporosis at present.
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spelling pubmed-100361932023-03-24 End to End Multitask Joint Learning Model for Osteoporosis Classification in CT Images Zhang, Kun Lin, Pengcheng Pan, Jing Xu, Peixia Qiu, Xuechen Crookes, Danny Hua, Liang Wang, Lin Comput Intell Neurosci Research Article Osteoporosis is a significant global health concern that can be difficult to detect early due to a lack of symptoms. At present, the examination of osteoporosis depends mainly on methods containing dual-energyX-ray, quantitative CT, etc., which are high costs in terms of equipment and human time. Therefore, a more efficient and economical method is urgently needed for diagnosing osteoporosis. With the development of deep learning, automatic diagnosis models for various diseases have been proposed. However, the establishment of these models generally requires images with only lesion areas, and annotating the lesion areas is time-consuming. To address this challenge, we propose a joint learning framework for osteoporosis diagnosis that combines localization, segmentation, and classification to enhance diagnostic accuracy. Our method includes a boundary heat map regression branch for thinning segmentation and a gated convolution module for adjusting context features in the classification module. We also integrate segmentation and classification features and propose a feature fusion module to adjust the weight of different levels of vertebrae. We trained our model on a self-built dataset and achieved an overall accuracy rate of 93.3% for the three label categories (normal, osteopenia, and osteoporosis) in the testing datasets. The area under the curve for the normal category is 0.973; for the osteopenia category, it is 0.965; and for the osteoporosis category, it is 0.985. Our method provides a promising alternative for the diagnosis of osteoporosis at present. Hindawi 2023-03-15 /pmc/articles/PMC10036193/ /pubmed/36970245 http://dx.doi.org/10.1155/2023/3018320 Text en Copyright © 2023 Kun Zhang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhang, Kun
Lin, Pengcheng
Pan, Jing
Xu, Peixia
Qiu, Xuechen
Crookes, Danny
Hua, Liang
Wang, Lin
End to End Multitask Joint Learning Model for Osteoporosis Classification in CT Images
title End to End Multitask Joint Learning Model for Osteoporosis Classification in CT Images
title_full End to End Multitask Joint Learning Model for Osteoporosis Classification in CT Images
title_fullStr End to End Multitask Joint Learning Model for Osteoporosis Classification in CT Images
title_full_unstemmed End to End Multitask Joint Learning Model for Osteoporosis Classification in CT Images
title_short End to End Multitask Joint Learning Model for Osteoporosis Classification in CT Images
title_sort end to end multitask joint learning model for osteoporosis classification in ct images
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036193/
https://www.ncbi.nlm.nih.gov/pubmed/36970245
http://dx.doi.org/10.1155/2023/3018320
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