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The utility of a type 2 diabetes polygenic score in addition to clinical variables for prediction of type 2 diabetes incidence in birth, youth and adult cohorts in an Indigenous study population
AIMS/HYPOTHESIS: There is limited information on how polygenic scores (PSs), based on variants from genome-wide association studies (GWASs) of type 2 diabetes, add to clinical variables in predicting type 2 diabetes incidence, particularly in non-European-ancestry populations. METHODS: For participa...
Autores principales: | Wedekind, Lauren E., Mahajan, Anubha, Hsueh, Wen-Chi, Chen, Peng, Olaiya, Muideen T., Kobes, Sayuko, Sinha, Madhumita, Baier, Leslie J., Knowler, William C., McCarthy, Mark I., Hanson, Robert L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036431/ https://www.ncbi.nlm.nih.gov/pubmed/36862161 http://dx.doi.org/10.1007/s00125-023-05870-2 |
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