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MACF1 overexpression in BMSCs alleviates senile osteoporosis in mice through TCF4/miR-335–5p signaling pathway

BACKGROUND: The decreased osteogenic differentiation ability of mesenchymal stem cells (MSCs) is one of the important reasons for SOP. Inhibition of Wnt signaling in MSCs is closely related to SOP. Microtubule actin crosslinking factor 1 (MACF1) is an important regulator in Wnt/β-catenin signal tran...

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Detalles Bibliográficos
Autores principales: Zhang, Kewen, Qiu, Wuxia, Li, Hui, Li, Jun, Wang, Pai, Chen, Zhihao, Lin, Xiao, Qian, Airong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036500/
https://www.ncbi.nlm.nih.gov/pubmed/36969134
http://dx.doi.org/10.1016/j.jot.2023.02.003