Colorimetric ortho-aminobenzaldehyde assay developed for the high-throughput chemical screening of inhibitors against dihydrodipicolinate synthase from pathogenic bacteria

In search of a new class of antibacterial agents, compounds that target the essential bacterial enzyme, dihydrodipicolinate synthase (DHDPS), are of interest to drug discovery efforts. DHDPS catalyzes the first committed step in the diaminopimelate (DAP) pathway to the biosynthesis of lysine in bact...

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Detalles Bibliográficos
Autor principal: Mitsakos, Voula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036502/
https://www.ncbi.nlm.nih.gov/pubmed/36967940
http://dx.doi.org/10.1016/j.heliyon.2023.e14304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036502/
https://www.ncbi.nlm.nih.gov/pubmed/36967940
http://dx.doi.org/10.1016/j.heliyon.2023.e14304

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