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Mena regulates nesprin-2 to control actin–nuclear lamina associations, trans-nuclear membrane signalling and gene expression

Interactions between cells and the extracellular matrix, mediated by integrin adhesion complexes, play key roles in fundamental cellular processes, including the sensing and transduction of mechanical cues. Here, we investigate systems-level changes in the integrin adhesome in patient-derived cutane...

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Detalles Bibliográficos
Autores principales: Li Mow Chee, Frederic, Beernaert, Bruno, Griffith, Billie G. C., Loftus, Alexander E. P., Kumar, Yatendra, Wills, Jimi C., Lee, Martin, Valli, Jessica, Wheeler, Ann P., Armstrong, J. Douglas, Parsons, Maddy, Leigh, Irene M., Proby, Charlotte M., von Kriegsheim, Alex, Bickmore, Wendy A., Frame, Margaret C., Byron, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036544/
https://www.ncbi.nlm.nih.gov/pubmed/36959177
http://dx.doi.org/10.1038/s41467-023-37021-x