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Targeting CLDN18.2 in cancers of the gastrointestinal tract: New drugs and new indications

Cancers of the gastrointestinal (GI) tract greatly contribute to the global cancer burden and cancer-related death. Claudin-18.2(CLDN18.2), a transmembrane protein, is a major component of tight junctions and plays an important role in the maintenance of barrier function. Its characteristic widespre...

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Detalles Bibliográficos
Autores principales: Chen, Jinxia, Xu, Zhiyuan, Hu, Can, Zhang, Shengjie, Zi, Mengli, Yuan, Li, Cheng, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036590/
https://www.ncbi.nlm.nih.gov/pubmed/36969060
http://dx.doi.org/10.3389/fonc.2023.1132319