Cargando…

Weakly supervised deep learning to predict recurrence in low-grade endometrial cancer from multiplexed immunofluorescence images

Predicting recurrence in low-grade, early-stage endometrial cancer (EC) is both challenging and clinically relevant. We present a weakly-supervised deep learning framework, NaroNet, that can learn, without manual expert annotation, the complex tumor-immune interrelations at three levels: local pheno...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiménez-Sánchez, Daniel, López-Janeiro, Álvaro, Villalba-Esparza, María, Ariz, Mikel, Kadioglu, Ece, Masetto, Ivan, Goubert, Virginie, Lozano, Maria D., Melero, Ignacio, Hardisson, David, Ortiz-de-Solórzano, Carlos, de Andrea, Carlos E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036616/ https://www.ncbi.nlm.nih.gov/pubmed/36959234 http://dx.doi.org/10.1038/s41746-023-00795-x

Ejemplares similares

The association between the tumor immune microenvironments and clinical outcome in low‐grade, early‐stage endometrial cancer patients
por: López‐Janeiro, Álvaro, et al.
Publicado: (2022)

Proteomic Analysis of Low-Grade, Early-Stage Endometrial Carcinoma Reveals New Dysregulated Pathways Associated with Cell Death and Cell Signaling
por: López-Janeiro, Álvaro, et al.
Publicado: (2021)

NaroNet: Discovery of tumor microenvironment elements from highly multiplexed images
por: Jiménez-Sánchez, Daniel, et al.
Publicado: (2022)

Comparison of multiplex, ELISA and immunofluorescence for detecting autoantibodies in JIA patients
por: Fawcett, Paul T, et al.
Publicado: (2012)

Challenges and Opportunities in the Statistical Analysis of Multiplex Immunofluorescence Data
por: Wilson, Christopher M., et al.
Publicado: (2021)

Cell segmentation for immunofluorescence multiplexed images using two-stage domain adaptation and weakly labeled data for pre-training
por: Han, Wenchao, et al.
Publicado: (2022)

Towards multiplexed immunofluorescence of 3D tissues
por: Cho, Wonjin, et al.
Publicado: (2023)

Development and multimodal characterization of an elastase-induced emphysema mouse disease model for the COPD frequent bacterial exacerbator phenotype
por: Rodríguez-Arce, Irene, et al.
Publicado: (2021)

Practical Weak Supervision
por: Tok, Wee, et al.
Publicado: (2021)

Best Practices for Technical Reproducibility Assessment of Multiplex Immunofluorescence
por: Laberiano-Fernández, Caddie, et al.
Publicado: (2021)

Multiplex Immunofluorescence: A Powerful Tool in Cancer Immunotherapy
por: Sheng, Wenjie, et al.
Publicado: (2023)

The use of mixed collagen-Matrigel matrices of increasing complexity recapitulates the biphasic role of cell adhesion in cancer cell migration: ECM sensing, remodeling and forces at the leading edge of cancer invasion
por: Anguiano, María, et al.
Publicado: (2020)

Validation of multiplex immunofluorescence for use in analysis of tumour infiltrating lymphocytes
por: Galetta, Henry, et al.
Publicado: (2015)

Overview of multiplex immunohistochemistry/immunofluorescence techniques in the era of cancer immunotherapy
por: Tan, Wei Chang Colin, et al.
Publicado: (2020)

Characterizing the Tumor Immune Microenvironment with Tyramide-Based Multiplex Immunofluorescence
por: Mori, Hidetoshi, et al.
Publicado: (2021)

Quantifying and correcting slide-to-slide variation in multiplexed immunofluorescence images
por: Harris, Coleman R, et al.
Publicado: (2022)

Improvement of Opal Multiplex Immunofluorescence Workflow for Human Tissue Sections
por: Willemsen, Marcella, et al.
Publicado: (2021)

Immunofluorescence versus xTAG multiplex PCR for the detection of respiratory picornavirus infections in children
por: Schindera, Christina, et al.
Publicado: (2010)

Choice of Illumination System & Fluorophore for Multiplex Immunofluorescence on FFPE Tissue Sections
por: Prost, Sandrine, et al.
Publicado: (2016)

Editorial: Multiplex Immunohistochemistry/Immunofluorescence Technique: The Potential and Promise for Clinical Application
por: Fincham, Rachel Elizabeth Ann, et al.
Publicado: (2022)

Validation of an Accurate Automated Multiplex Immunofluorescence Method for Immuno-Profiling Melanoma
por: Yaseen, Zarwa, et al.
Publicado: (2022)

Multiplex Protein Imaging through PACIFIC: Photoactive Immunofluorescence with Iterative Cleavage
por: Ji, Fei, et al.
Publicado: (2023)

Machine-based method for multiplex in situ molecular characterization of tissues by immunofluorescence detection
por: Yarilin, Dmitry, et al.
Publicado: (2015)

Pathology Quality Control for Multiplex Immunofluorescence and Image Analysis Assessment in Longitudinal Studies
por: Lazcano, Rossana, et al.
Publicado: (2021)

Multi-institutional TSA-amplified Multiplexed Immunofluorescence Reproducibility Evaluation (MITRE) Study
por: Taube, Janis M, et al.
Publicado: (2021)

Companion diagnostic requirements for spatial biology using multiplex immunofluorescence and multispectral imaging
por: Locke, Darren, et al.
Publicado: (2023)

Protocol for multimodal analysis of human kidney tissue by imaging mass spectrometry and CODEX multiplexed immunofluorescence
por: Neumann, Elizabeth K., et al.
Publicado: (2021)

Weakly Supervised Violence Detection in Surveillance Video
por: Choqueluque-Roman, David, et al.
Publicado: (2022)

Weakly supervised end-to-end artificial intelligence in gastrointestinal endoscopy
por: Buendgens, Lukas, et al.
Publicado: (2022)

Combining weakly and strongly supervised learning improves strong supervision in Gleason pattern classification
por: Otálora, Sebastian, et al.
Publicado: (2021)

Phenotypic Analysis of Diseased Plant Leaves Using Supervised and Weakly Supervised Deep Learning
por: Zhou, Lei, et al.
Publicado: (2023)

A robust multiplex immunofluorescence and digital pathology workflow for the characterisation of the tumour immune microenvironment
por: Viratham Pulsawatdi, Amélie, et al.
Publicado: (2020)

Cargo and cell-specific differences in extracellular vesicle populations identified by multiplexed immunofluorescent analysis
por: Burbidge, Kevin, et al.
Publicado: (2020)

Oligonucleotide conjugated antibodies permit highly multiplexed immunofluorescence for future use in clinical histopathology
por: McMahon, Nathan P., et al.
Publicado: (2020)

Multiplex immunofluorescence-guided laser capture microdissection for spatial transcriptomics of metastatic melanoma tissues
por: Martinek, Jan, et al.
Publicado: (2022)

Snorkel: rapid training data creation with weak supervision
por: Ratner, Alexander, et al.
Publicado: (2019)

Weakly-supervised deep learning models in computational pathology
por: Augustine, Tanya N.
Publicado: (2022)

Spatio-Frequency Decoupled Weak-Supervision for Face Reconstruction
por: Li, Yanyan, et al.
Publicado: (2022)

Robust Semi-Supervised Traffic Sign Recognition via Self-Training and Weakly-Supervised Learning
por: Nartey, Obed Tettey, et al.
Publicado: (2020)

Supervised and Weakly Supervised Deep Learning for Segmentation and Counting of Cotton Bolls Using Proximal Imagery
por: Adke, Shrinidhi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0spqd6s5765o0ogng68vjmpsv1