The K/HDEL receptor does not recycle but instead acts as a Golgi-gatekeeper

Accurately measuring the ability of the K/HDEL receptor (ERD2) to retain the ER cargo Amy-HDEL has questioned earlier results on which the popular receptor recycling model is based upon. Here we demonstrate that ERD2 Golgi-retention, rather than fast ER export supports its function. Ligand-induced E...

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Detalles Bibliográficos
Autores principales: Alvim, Jonas C., Bolt, Robert M., An, Jing, Kamisugi, Yasuko, Cuming, Andrew, Silva-Alvim, Fernanda A. L., Concha, Juan O., daSilva, Luis L. P., Hu, Meiyi, Hirsz, Dominique, Denecke, Jurgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036638/
https://www.ncbi.nlm.nih.gov/pubmed/36959220
http://dx.doi.org/10.1038/s41467-023-37056-0

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