ER stress induces upregulation of transcription factor Tbx20 and downstream Bmp2 signaling to promote cardiomyocyte survival

In the mammalian heart, fetal cardiomyocytes proliferate prior to birth; however, they exit the cell cycle shortly after birth. Recent studies show that adult cardiomyocytes re-enters the cell cycle postinjury to promote cardiac regeneration. The endoplasmic reticulum (ER) orchestrates the productio...

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Detalles Bibliográficos
Autores principales: Das, Shreya, Mondal, Arunima, Dey, Chandrani, Chakraborty, Santanu, Bhowmik, Rudranil, Karmakar, Sanmoy, Sengupta, Arunima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036653/
https://www.ncbi.nlm.nih.gov/pubmed/36805334
http://dx.doi.org/10.1016/j.jbc.2023.103031

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