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Critical Appraisal of Current Acute LBP Management and the Role of a Multimodal Analgesia: A Narrative Review

Acute low back pain (LBP) stands as a leading cause of activity limitation and work absenteeism, and its associated healthcare expenditures are expected to become substantial when acute LBP develops into a chronic and even refractory condition. Therefore, early intervention is crucial to prevent pro...

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Detalles Bibliográficos
Autores principales: Hanna, Magdi, Perrot, Serge, Varrassi, Giustino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036717/
https://www.ncbi.nlm.nih.gov/pubmed/36765012
http://dx.doi.org/10.1007/s40122-023-00479-0
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author Hanna, Magdi
Perrot, Serge
Varrassi, Giustino
author_facet Hanna, Magdi
Perrot, Serge
Varrassi, Giustino
author_sort Hanna, Magdi
collection PubMed
description Acute low back pain (LBP) stands as a leading cause of activity limitation and work absenteeism, and its associated healthcare expenditures are expected to become substantial when acute LBP develops into a chronic and even refractory condition. Therefore, early intervention is crucial to prevent progression to chronic pain, for which the management is particularly challenging and the most effective pharmacological therapy is still controversial. Current guideline treatment recommendations vary and are mostly driven by expertise with opinion differing across different interventions. Thus, it is difficult to formulate evidence-based guidance when the relatively few randomized clinical trials have explored the diagnosis and management of LBP while employing different selection criteria, statistical analyses, and outcome measurements. This narrative review aims to provide a critical appraisal of current acute LBP management by discussing the unmet needs and areas of improvement from bench-to-bedside, and proposes multimodal analgesia as the way forward to attain an effective and prolonged pain relief and functional recovery in patients with acute LBP.
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spelling pubmed-100367172023-03-25 Critical Appraisal of Current Acute LBP Management and the Role of a Multimodal Analgesia: A Narrative Review Hanna, Magdi Perrot, Serge Varrassi, Giustino Pain Ther Review Acute low back pain (LBP) stands as a leading cause of activity limitation and work absenteeism, and its associated healthcare expenditures are expected to become substantial when acute LBP develops into a chronic and even refractory condition. Therefore, early intervention is crucial to prevent progression to chronic pain, for which the management is particularly challenging and the most effective pharmacological therapy is still controversial. Current guideline treatment recommendations vary and are mostly driven by expertise with opinion differing across different interventions. Thus, it is difficult to formulate evidence-based guidance when the relatively few randomized clinical trials have explored the diagnosis and management of LBP while employing different selection criteria, statistical analyses, and outcome measurements. This narrative review aims to provide a critical appraisal of current acute LBP management by discussing the unmet needs and areas of improvement from bench-to-bedside, and proposes multimodal analgesia as the way forward to attain an effective and prolonged pain relief and functional recovery in patients with acute LBP. Springer Healthcare 2023-02-10 2023-04 /pmc/articles/PMC10036717/ /pubmed/36765012 http://dx.doi.org/10.1007/s40122-023-00479-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Review
Hanna, Magdi
Perrot, Serge
Varrassi, Giustino
Critical Appraisal of Current Acute LBP Management and the Role of a Multimodal Analgesia: A Narrative Review
title Critical Appraisal of Current Acute LBP Management and the Role of a Multimodal Analgesia: A Narrative Review
title_full Critical Appraisal of Current Acute LBP Management and the Role of a Multimodal Analgesia: A Narrative Review
title_fullStr Critical Appraisal of Current Acute LBP Management and the Role of a Multimodal Analgesia: A Narrative Review
title_full_unstemmed Critical Appraisal of Current Acute LBP Management and the Role of a Multimodal Analgesia: A Narrative Review
title_short Critical Appraisal of Current Acute LBP Management and the Role of a Multimodal Analgesia: A Narrative Review
title_sort critical appraisal of current acute lbp management and the role of a multimodal analgesia: a narrative review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036717/
https://www.ncbi.nlm.nih.gov/pubmed/36765012
http://dx.doi.org/10.1007/s40122-023-00479-0
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