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Targeting Notch1-YAP Circuit Reprograms Macrophage Polarization and Alleviates Acute Liver Injury in Mice

BACKGROUND & AIMS: Hepatic immune system disorder plays a critical role in the pathogenesis of acute liver injury. The intrinsic signaling mechanisms responsible for dampening excessive activation of liver macrophages are not completely understood. The Notch and Hippo-YAP signaling pathways have...

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Detalles Bibliográficos
Autores principales:	Yang, Yan, Ni, Ming, Zong, Ruobin, Yu, Mengxue, Sun, Yishuang, Li, Jiahui, Chen, Pu, Li, Changyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036742/ https://www.ncbi.nlm.nih.gov/pubmed/36706917 http://dx.doi.org/10.1016/j.jcmgh.2023.01.002

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