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Protective effects of intrathecal injection of AAV9-RabGGTB-GFP(+) in SOD1(G93A) mice

INTRODUCTION: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that widely affects motor neurons of the CNS. About 20% of patients with ALS have familial ALS (fALS). One of the classic models of ALS are SOD1(G93A) mice. Misfolded SOD1 protein can be overexpressed in motor neurons,...

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Detalles Bibliográficos
Autores principales:	Gao, Tianchu, Huo, Jia, Xin, Cheng, Yang, Jing, Liu, Qi, Dong, Hui, Li, Rui, Liu, Yaling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Aging Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036913/ https://www.ncbi.nlm.nih.gov/pubmed/36967828 http://dx.doi.org/10.3389/fnagi.2023.1092607

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