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Scleral Proteome in Noninfectious Scleritis Unravels Upregulation of Filaggrin-2 and Signs of Neovascularization

PURPOSE: Scleritis is a severe inflammatory ocular disorder with unknown pathogenesis. We investigated healthy sclera as well as sclera affected by noninfectious scleritis for differentially expressed proteins using a mass spectrometry approach. METHODS: We collected scleral samples of enucleated ey...

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Detalles Bibliográficos
Autores principales: Vergouwen, Daphne P. C., Ten Berge, Josianne C., Guzel, Coskun, van den Bosch, Thierry P. P., Verdijk, Robert M., Rothova, Aniki, Luider, Theo M., Schreurs, Marco W. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10036950/
https://www.ncbi.nlm.nih.gov/pubmed/36930145
http://dx.doi.org/10.1167/iovs.64.3.27