Single-cell profiling identifies a novel human polyclonal unconventional T cell lineage

In the human thymus, a CD10(+) PD-1(+) TCRαβ(+) differentiation pathway diverges from the conventional single positive T cell lineages at the early double-positive stage. Here, we identify the progeny of this unconventional lineage in antigen-inexperienced blood. These unconventional T cells (UTCs)...

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Detalles Bibliográficos
Autores principales: Billiet, Lore, De Cock, Laurenz, Sanchez Sanchez, Guillem, Mayer, Rupert L., Goetgeluk, Glenn, De Munter, Stijn, Pille, Melissa, Ingels, Joline, Jansen, Hanne, Weening, Karin, Pascal, Eva, Raes, Killian, Bonte, Sarah, Kerre, Tessa, Vandamme, Niels, Seurinck, Ruth, Roels, Jana, Lavaert, Marieke, Van Nieuwerburgh, Filip, Leclercq, Georges, Taghon, Tom, Impens, Francis, Menten, Björn, Vermijlen, David, Vandekerckhove, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037106/
https://www.ncbi.nlm.nih.gov/pubmed/36939517
http://dx.doi.org/10.1084/jem.20220942

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