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High-Throughput Screen Reveals the Structure–Activity Relationship of the Antimicrobial Lasso Peptide Ubonodin

[Image: see text] The Burkholderia cepacia complex (Bcc) is a group of bacteria including opportunistic human pathogens. Immunocompromised individuals and cystic fibrosis patients are especially vulnerable to serious infections by these bacteria, motivating the search for compounds with antimicrobia...

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Detalles Bibliográficos
Autores principales: Thokkadam, Alina, Do, Truc, Ran, Xinchun, Brynildsen, Mark P., Yang, Zhongyue J., Link, A. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037499/
https://www.ncbi.nlm.nih.gov/pubmed/36968541
http://dx.doi.org/10.1021/acscentsci.2c01487