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Insights into Online microRNA Bioinformatics Tools
MicroRNAs (miRNAs) are members of the small non-coding RNA family regulating gene expression at the post-transcriptional level. MiRNAs have been found to have critical roles in various biological and pathological processes. Research in this field has significantly progressed, with increased recognit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037614/ https://www.ncbi.nlm.nih.gov/pubmed/36960963 http://dx.doi.org/10.3390/ncrna9020018 |
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author | Luna Buitrago, Diana Lovering, Ruth C. Caporali, Andrea |
author_facet | Luna Buitrago, Diana Lovering, Ruth C. Caporali, Andrea |
author_sort | Luna Buitrago, Diana |
collection | PubMed |
description | MicroRNAs (miRNAs) are members of the small non-coding RNA family regulating gene expression at the post-transcriptional level. MiRNAs have been found to have critical roles in various biological and pathological processes. Research in this field has significantly progressed, with increased recognition of the importance of miRNA regulation. As a result of the vast data and information available regarding miRNAs, numerous online tools have emerged to address various biological questions related to their function and influence across essential cellular processes. This review includes a brief introduction to available resources for an investigation covering aspects such as miRNA sequences, target prediction/validation, miRNAs associated with disease, pathway analysis and genetic variants within miRNAs. |
format | Online Article Text |
id | pubmed-10037614 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100376142023-03-25 Insights into Online microRNA Bioinformatics Tools Luna Buitrago, Diana Lovering, Ruth C. Caporali, Andrea Noncoding RNA Review MicroRNAs (miRNAs) are members of the small non-coding RNA family regulating gene expression at the post-transcriptional level. MiRNAs have been found to have critical roles in various biological and pathological processes. Research in this field has significantly progressed, with increased recognition of the importance of miRNA regulation. As a result of the vast data and information available regarding miRNAs, numerous online tools have emerged to address various biological questions related to their function and influence across essential cellular processes. This review includes a brief introduction to available resources for an investigation covering aspects such as miRNA sequences, target prediction/validation, miRNAs associated with disease, pathway analysis and genetic variants within miRNAs. MDPI 2023-03-06 /pmc/articles/PMC10037614/ /pubmed/36960963 http://dx.doi.org/10.3390/ncrna9020018 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Luna Buitrago, Diana Lovering, Ruth C. Caporali, Andrea Insights into Online microRNA Bioinformatics Tools |
title | Insights into Online microRNA Bioinformatics Tools |
title_full | Insights into Online microRNA Bioinformatics Tools |
title_fullStr | Insights into Online microRNA Bioinformatics Tools |
title_full_unstemmed | Insights into Online microRNA Bioinformatics Tools |
title_short | Insights into Online microRNA Bioinformatics Tools |
title_sort | insights into online microrna bioinformatics tools |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037614/ https://www.ncbi.nlm.nih.gov/pubmed/36960963 http://dx.doi.org/10.3390/ncrna9020018 |
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