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Insights into Online microRNA Bioinformatics Tools

MicroRNAs (miRNAs) are members of the small non-coding RNA family regulating gene expression at the post-transcriptional level. MiRNAs have been found to have critical roles in various biological and pathological processes. Research in this field has significantly progressed, with increased recognit...

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Detalles Bibliográficos
Autores principales: Luna Buitrago, Diana, Lovering, Ruth C., Caporali, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037614/
https://www.ncbi.nlm.nih.gov/pubmed/36960963
http://dx.doi.org/10.3390/ncrna9020018
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author Luna Buitrago, Diana
Lovering, Ruth C.
Caporali, Andrea
author_facet Luna Buitrago, Diana
Lovering, Ruth C.
Caporali, Andrea
author_sort Luna Buitrago, Diana
collection PubMed
description MicroRNAs (miRNAs) are members of the small non-coding RNA family regulating gene expression at the post-transcriptional level. MiRNAs have been found to have critical roles in various biological and pathological processes. Research in this field has significantly progressed, with increased recognition of the importance of miRNA regulation. As a result of the vast data and information available regarding miRNAs, numerous online tools have emerged to address various biological questions related to their function and influence across essential cellular processes. This review includes a brief introduction to available resources for an investigation covering aspects such as miRNA sequences, target prediction/validation, miRNAs associated with disease, pathway analysis and genetic variants within miRNAs.
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spelling pubmed-100376142023-03-25 Insights into Online microRNA Bioinformatics Tools Luna Buitrago, Diana Lovering, Ruth C. Caporali, Andrea Noncoding RNA Review MicroRNAs (miRNAs) are members of the small non-coding RNA family regulating gene expression at the post-transcriptional level. MiRNAs have been found to have critical roles in various biological and pathological processes. Research in this field has significantly progressed, with increased recognition of the importance of miRNA regulation. As a result of the vast data and information available regarding miRNAs, numerous online tools have emerged to address various biological questions related to their function and influence across essential cellular processes. This review includes a brief introduction to available resources for an investigation covering aspects such as miRNA sequences, target prediction/validation, miRNAs associated with disease, pathway analysis and genetic variants within miRNAs. MDPI 2023-03-06 /pmc/articles/PMC10037614/ /pubmed/36960963 http://dx.doi.org/10.3390/ncrna9020018 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Luna Buitrago, Diana
Lovering, Ruth C.
Caporali, Andrea
Insights into Online microRNA Bioinformatics Tools
title Insights into Online microRNA Bioinformatics Tools
title_full Insights into Online microRNA Bioinformatics Tools
title_fullStr Insights into Online microRNA Bioinformatics Tools
title_full_unstemmed Insights into Online microRNA Bioinformatics Tools
title_short Insights into Online microRNA Bioinformatics Tools
title_sort insights into online microrna bioinformatics tools
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037614/
https://www.ncbi.nlm.nih.gov/pubmed/36960963
http://dx.doi.org/10.3390/ncrna9020018
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