Cargando…
Repeated Lung Ultrasound versus Chest X-ray—Which One Predicts Better Clinical Outcome in COVID-19?
The purpose of this study was to evaluate whether changes in repeated lung ultrasound (LUS) or chest X-ray (CXR) of coronavirus disease 2019 (COVID-19) patients can predict the development of severe disease and the need for treatment in the intensive care unit (ICU). In this prospective monocentric...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037641/ https://www.ncbi.nlm.nih.gov/pubmed/36961015 http://dx.doi.org/10.3390/tomography9020056 |
_version_ | 1784911928289656832 |
---|---|
author | Spogis, Jakob Fusco, Stefano Hagen, Florian Kaufmann, Sascha Malek, Nisar Hoffmann, Tatjana |
author_facet | Spogis, Jakob Fusco, Stefano Hagen, Florian Kaufmann, Sascha Malek, Nisar Hoffmann, Tatjana |
author_sort | Spogis, Jakob |
collection | PubMed |
description | The purpose of this study was to evaluate whether changes in repeated lung ultrasound (LUS) or chest X-ray (CXR) of coronavirus disease 2019 (COVID-19) patients can predict the development of severe disease and the need for treatment in the intensive care unit (ICU). In this prospective monocentric study, COVID-19 patients received standardized LUS and CXR at day 1, 3 and 5. Scores for changes in LUS (LUS score) and CXR (RALE and M-RALE) were calculated and compared. Intra-class correlation was calculated for two readers of CXR and ROC analysis to evaluate the best discriminator for the need for ICU treatment. A total of 30 patients were analyzed, 26 patients with follow-up LUS and CXR. Increase in M-RALE between baseline and follow-up 1 was significantly higher in patients with need for ICU treatment in the further hospital stay (p = 0.008). Both RALE and M-RALE significantly correlated with LUS score (r = 0.5, p < 0.0001). ROC curves with need for ICU treatment as separator were not significantly different for changes in M-RALE (AUC: 0.87) and LUS score (AUC: 0.79), both being good discriminators. ICC was moderate for RALE (0.56) and substantial for M-RALE (0.74). The present study demonstrates that both follow-up LUS and CXR are powerful tools to track the evolution of COVID-19, and can be used equally as predictors for the need for ICU treatment. |
format | Online Article Text |
id | pubmed-10037641 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100376412023-03-25 Repeated Lung Ultrasound versus Chest X-ray—Which One Predicts Better Clinical Outcome in COVID-19? Spogis, Jakob Fusco, Stefano Hagen, Florian Kaufmann, Sascha Malek, Nisar Hoffmann, Tatjana Tomography Article The purpose of this study was to evaluate whether changes in repeated lung ultrasound (LUS) or chest X-ray (CXR) of coronavirus disease 2019 (COVID-19) patients can predict the development of severe disease and the need for treatment in the intensive care unit (ICU). In this prospective monocentric study, COVID-19 patients received standardized LUS and CXR at day 1, 3 and 5. Scores for changes in LUS (LUS score) and CXR (RALE and M-RALE) were calculated and compared. Intra-class correlation was calculated for two readers of CXR and ROC analysis to evaluate the best discriminator for the need for ICU treatment. A total of 30 patients were analyzed, 26 patients with follow-up LUS and CXR. Increase in M-RALE between baseline and follow-up 1 was significantly higher in patients with need for ICU treatment in the further hospital stay (p = 0.008). Both RALE and M-RALE significantly correlated with LUS score (r = 0.5, p < 0.0001). ROC curves with need for ICU treatment as separator were not significantly different for changes in M-RALE (AUC: 0.87) and LUS score (AUC: 0.79), both being good discriminators. ICC was moderate for RALE (0.56) and substantial for M-RALE (0.74). The present study demonstrates that both follow-up LUS and CXR are powerful tools to track the evolution of COVID-19, and can be used equally as predictors for the need for ICU treatment. MDPI 2023-03-21 /pmc/articles/PMC10037641/ /pubmed/36961015 http://dx.doi.org/10.3390/tomography9020056 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Spogis, Jakob Fusco, Stefano Hagen, Florian Kaufmann, Sascha Malek, Nisar Hoffmann, Tatjana Repeated Lung Ultrasound versus Chest X-ray—Which One Predicts Better Clinical Outcome in COVID-19? |
title | Repeated Lung Ultrasound versus Chest X-ray—Which One Predicts Better Clinical Outcome in COVID-19? |
title_full | Repeated Lung Ultrasound versus Chest X-ray—Which One Predicts Better Clinical Outcome in COVID-19? |
title_fullStr | Repeated Lung Ultrasound versus Chest X-ray—Which One Predicts Better Clinical Outcome in COVID-19? |
title_full_unstemmed | Repeated Lung Ultrasound versus Chest X-ray—Which One Predicts Better Clinical Outcome in COVID-19? |
title_short | Repeated Lung Ultrasound versus Chest X-ray—Which One Predicts Better Clinical Outcome in COVID-19? |
title_sort | repeated lung ultrasound versus chest x-ray—which one predicts better clinical outcome in covid-19? |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037641/ https://www.ncbi.nlm.nih.gov/pubmed/36961015 http://dx.doi.org/10.3390/tomography9020056 |
work_keys_str_mv | AT spogisjakob repeatedlungultrasoundversuschestxraywhichonepredictsbetterclinicaloutcomeincovid19 AT fuscostefano repeatedlungultrasoundversuschestxraywhichonepredictsbetterclinicaloutcomeincovid19 AT hagenflorian repeatedlungultrasoundversuschestxraywhichonepredictsbetterclinicaloutcomeincovid19 AT kaufmannsascha repeatedlungultrasoundversuschestxraywhichonepredictsbetterclinicaloutcomeincovid19 AT maleknisar repeatedlungultrasoundversuschestxraywhichonepredictsbetterclinicaloutcomeincovid19 AT hoffmanntatjana repeatedlungultrasoundversuschestxraywhichonepredictsbetterclinicaloutcomeincovid19 |