Sustained Intratumoral Administration of Agonist CD40 Antibody Overcomes Immunosuppressive Tumor Microenvironment in Pancreatic Cancer

Agonist CD40 monoclonal antibodies (mAb) is a promising immunotherapeutic agent for cold‐to‐hot tumor immune microenvironment (TIME) conversion. Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and lethal cancer known as an immune desert, and therefore urgently needs more effective treatment...

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Detalles Bibliográficos
Autores principales: Liu, Hsuan‐Chen, Davila Gonzalez, Daniel, Viswanath, Dixita Ishani, Vander Pol, Robin Shae, Saunders, Shani Zakiya, Di Trani, Nicola, Xu, Yitian, Zheng, Junjun, Chen, Shu‐Hsia, Chua, Corrine Ying Xuan, Grattoni, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037694/
https://www.ncbi.nlm.nih.gov/pubmed/36658712
http://dx.doi.org/10.1002/advs.202206873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037694/
https://www.ncbi.nlm.nih.gov/pubmed/36658712
http://dx.doi.org/10.1002/advs.202206873

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