Overcoming the On‐Target Toxicity in Antibody‐Mediated Therapies via an Indirect Active Targeting Strategy

Antibody‐based therapies could be led astray when target receptors are expressed on nontarget sites, and the on‐target toxicity poses critical challenges to clinical applications. Here, a biomimetic indirect active targeting (INTACT) strategy is proposed based on receptor expression disparities betw...

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Detalles Bibliográficos
Autores principales: Tang, Zhongjie, Wang, Xiaoyou, Tang, Mei, Wu, Jin, Zhang, Jiexuan, Liu, Xinlong, Gao, Feiyan, Fu, Yu, Tang, Peng, Li, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037698/
https://www.ncbi.nlm.nih.gov/pubmed/36683161
http://dx.doi.org/10.1002/advs.202206912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10037698/
https://www.ncbi.nlm.nih.gov/pubmed/36683161
http://dx.doi.org/10.1002/advs.202206912

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